Spravato FAQ

Spravato works by targeting the brain's glutamate system, a different mechanism than most traditional antidepressants, which typically affect serotonin, norepinephrine, and dopamine. By increasing glutamate levels, Spravato promotes the formation of new synaptic connections in the brain, potentially leading to rapid improvement in depressive symptoms.

Spravato is intended for adults with treatment-resistant depression, which means they have tried at least two different antidepressant treatments, each for an adequate duration, without sufficient relief. A thorough evaluation by a healthcare provider will determine if Spravato is suitable for you.

Spravato is administered as a nasal spray in a controlled medical setting. Each session typically lasts about two hours. After administering the nasal spray, you will be monitored for at least two hours by a healthcare professional to ensure your safety and manage any side effects.

During the initial phase of treatment, Spravato is usually administered twice a week for the first four weeks. Following this, the frequency is gradually reduced to once a week, and then possibly once every two weeks, depending on your response to the treatment and your healthcare provider's recommendations.

Common side effects of Spravato include dizziness, nausea, dissociation (a feeling of being disconnected from reality), headache, increased blood pressure, and drowsiness. These side effects are typically mild to moderate and usually diminish with time.

Many patients begin to notice improvement in their depressive symptoms within the first few treatment sessions. Some may experience relief within hours of the first dose. However, individual responses can vary, and it may take a few weeks to achieve the full benefits of the treatment.

Spravato is an FDA-approved treatment and has undergone rigorous clinical trials to establish its safety and efficacy. It is administered under the supervision of a healthcare professional to ensure patient safety and to manage any potential side effects.

Spravato is covered by most major insurances. We recommend contacting your insurance company to determine your specific coverage and any potential out-of-pocket costs. Our office can assist you with insurance verification.

To determine if Spravato is right for you, schedule a consultation with our office. Our compassionate team will conduct a thorough evaluation, discuss your treatment history, and develop a personalized treatment plan tailored to your needs.